Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model
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چکیده
منابع مشابه
Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model
There is a paucity of large animal models to study both the extent and the health risk of ionizing radiation exposure in humans. One promising candidate for such a model is the minipig. Here, we evaluate the minipig for its potential in γ-H2AX-based biodosimetry after exposure to ionizing radiation using both Cs137 and Co60 sources. γ-H2AX foci were enumerated in blood lymphocytes and normal fi...
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The first gamma-H2AX biodosimetry intercomparison exercise of the developing European biodosimetry network RENEB.
In the event of a mass casualty radiation incident, the gamma-H2AX foci assay could be a useful tool to estimate radiation doses received by individuals. The rapid processing time of blood samples of just a few hours and the potential for batch processing, enabling high throughput, make the assay ideal for early triage categorisation to separate the 'worried well' from the low and critically ex...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2013
ISSN: 1422-0067
DOI: 10.3390/ijms140714119